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Pharmacology G.I.T 4b4f2b6f

Drug of choice for prevention of NSAID induced peptic ulcer disease is

A
H2 receptor blockers
B
Proton pump inhibitors
C
Macrolide antibiotic
D
Sucralfate
High-Yield Explanation
Ans. is 'b' i.e., Proton pump inhibitors * PPI are the DOC for peptic ulcer (gastric or duodenal), GERD, ZE syndrome, prevention of aspiratory pneumonia and NSAID induced gastric / duodenal ulcers. Note - PGE1 analogue (Misoprostol) is specific drug for prevention and treatment of NSAID induced ulcer, but DOC is PPL

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