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Physiology General 4b2fda7a

Seoli cells have receptors for which of the following hormone?

A
FSH
B
LH
C
Inhibin
D
Progesterone
High-Yield Explanation
Seoli cells serve as "nurse" cells for spermatogenesis, nourishing germ cells as they develop. They also paicipate in germ cell phagocytosis. High-affinity FSH receptors exist on Seoli cells and FSH binding induces the production of androgen-binding protein, which is secreted into the tubular luminal fluid. By binding testosterone, androgen-binding protein ensures that high levels of androgen (20-50 times that of serum) exist within the seminiferous tubules. Ligand-receptor complexes, such as c-kit and kit ligand, may also mediate communication between germinal and Seoli cells. Ref: Turek P.J. (2008). Chapter 44. Male Infeility. In E.A. Tanagho, J.W. McAninch (Eds), Smith's General Urology, 17e.

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