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Unknown General 4b2941f4

Hyperacute rejection occurs within:

A
12 hours
B
2 weeks
C
1 month
D
3 months
High-Yield Explanation
Ref. Robbins Pathology. 9th edition. Page. 233   Hyperacute Rejection This form of rejection occurs within minutes or hours after transplantation. A hyperacutely rejecting kidney rapidly becomes cyanotic, mottled, and flaccid, and may excrete a mere few drops of bloody urine. Immunoglobulin and complement are deposited in the vessel wall, causing endothelial injury and fibrin-platelet thrombi Glomeruli undergo thrombotic occlusion of the capillaries, and fibrinoid necrosis occurs in arterial walls. The kidney cortex then under- goes outright necrosis (infarction), and such nonfunctioning kidneys have to be removed.

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