What is true about Histoplasmosis

Chronic (late stages) - Cavitary histoplasmosis so indistinguishable from T.B 1. Histoplasmosis or Darling's disease is caused by dimorphic fungus - Histoplasma capsulatum. 2. Transmission: By inhalation of spores (i.e. microconidia) circulating in the air being contaminated with soil. 3. Clinical Manifestations: - Pulmonary histoplasmosis: It is the most common form. Acute form stas as mild flu like illness Chronic - Cavitary histoplasmosis Mucocutaneous oral lesion (paicularly seen in Indian patients) Disseminated histoplasmosis develops if CMI is very low (HIV). 4. Histoplasma is a dimorphic fungus, hence Culture is the gold standard method of diagnosis