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Pathology All India exam 4aa31c8f

Which of the following congential anomalies is seen with maternal use of cocaine?

A
Sacral agenesis
B
Hydrops
C
Cerebral infarction
D
Hyperichosis
High-Yield Explanation
Cocaine - use has been associated with MI, arrhythmias aoic rupture, strokes seizures, bowel ischemia, hypehermia, and sudden death Risk of vascular disruption within the embryo-fetus or placenta is highest after the first trimester and likely accounts for the increased incidence of stillbihs A number of cocaine related congenital anomalies due to vascular based disruption, they include skull defect, cutis aplasia, porencephaly, ileal atresia, cardiac anomalies and visceral infarcts

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