A pt. has a pituitary tumour and pheochromocytoma and a thyroid nodule. Which Ca is most likely to occur -

This pt. is suffering from MEN Syndrome. MEN (Multiple endocrine neoplasias) or MEA (Multiple endocrine adenomatosis) syndromes are characterized by the familial occurrence of multiple endocrine neoplasms. 3 types of MEN Syndrome are recognized. a) MEN I (or Wermer's Syndrome*) consists of - Pituitary adenoma (or hyperplasia)* Parathyroid adenoma (or hyperplasia)* Pancreatic islet cell hyperplasia, adenoma or carcinoma Other less common manifestations : foregut carcinoids pheochromocytoma subcutaneous or visceral lipomas b) MEN HA ( or Sipple syndrome) Medullary carcinoma of thyroid (MCT)* Pheochromocytoma* Parathyroid adenoma (or hyperplasia)* Hirschsprung disease* Cutaneous lichen amyloidosis* c) MEN H B Medullary carcinoma of thyroid (MCT)* Pheochromocytoma * Marfanoid features* Mucocutaneous and gastrointestinal neuromas* Thus this pt. is suffering from MEN II A or II B syndrome (Pituitary tumor in this pt. is still confusing the question, but still; answer is definitely MCT).