The first ADA approved fluoride toothpaste in the year:

In 1955, the stannous fluoride dentifrice became the first dentifrice recognized by the Food and Drug Administration (FDA) as an effective tooth decay preventive product.  The first fluoride dentifrice was accepted by American Dental Association (ADA) in 1964. It is called CREST. Essentials of preventive and community dentistry Soben Peter 5th edition page no. 261