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Medicine General 4982eef9

A 29-year-old, 4 months pregnant primigravida has history of juvenile myoclonic epilepsy. She has been regularly taking sodium valproate and now presents requesting for an opinion for a change in her anti-epileptic treatment. What would you sugeets her?

A
Immediately taper off valproate and sta lamotrigine
B
Switch to carbamazepine
C
Continue valproate and serial drug monitoring in blood
D
Add lamotrigine to valproate
High-Yield Explanation
Answer: c. Continue valproate and serial drug monitoring in blood (Ref Harrison I9/e p2544, 18/e p3269)Continue valproate with serial drug monitoring in the blood of the 4-month old patient having history of juvenile myoclonic epilepsy.

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