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Pathology Cellular Pathology 4974b9cf

Cytokine causing fever -

A
IL-6
B
IFN-y
C
IL-18
D
EL-4
High-Yield Explanation
Ans. is 'a' i.e., IL-6 Pyrogeneso Pyrogenes are substances that cause fever,o Pyrogens may be exogenous or endogenousExogenous - Bacterial toxinsEndogenous - IL-1, TNF-a, IL-6, Interferons, Ciliory's neurotropic factoro These pyrogenes increase the level of PGE2 in the hypothalamus that elevates the thermoregulatory set point and causes fever.

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