Used in head injury

(C) Hypertonic saline # Initial management of HEAD INJURY:> Unconscious patients should be intubated and ventilated to maintain Po2 over 13.5 kPa and PCO2at 4.5-5.0 kPa.> Systemic blood pressure must be maintained normal or above normal to allow for good neurological outcome, initially by fluid resuscitation.> Glucose-containing solutions should be avoided.> Blood loss from other injuries should be replaced by blood products as usually.> Hypertonic saline solution (7.5%) may improve outcome in patients with multiple trauma because of its effect on ICP.> Extracranial injuries that threaten life should be treated before definitive neurosurgical treatment, but otherwise simply stabilized beforehand.