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Medicine General 4865abb7

Which is not seen in multiple myeloma :

A
Anemia
B
Increased alkaline phosphatase
C
Hypercalcemia
D
Increased ESR
High-Yield Explanation
Answer is B (Increased in alkaline phosphatase) Serum alkaline phosphatase is usually normal even with extensive bone involvement because of the absence of aslet)hractfr fictivity - Harrison 16th/ 659 Laboratory parameters in multiple myeloma : Anaemia: Normocytic normochromic ESR : markedly increased Hypogammaglobulinemiae Monoclonal spike on Serum protein electrophoresis - Monoclonal Gammopathy (M Band) Bone marrow replacement of normal marrow elements by plasma cells. Bence Jones Proteinuria: Light chain proteinuria (inclomplete IgG) Uric Acid level : Elevated due to increased cell turnover Serum calcium : Elevated Alkaline phosphatase : Normal Neutropenia & Thrombocytopenia rare

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