True statement about route of drug administration is: a) 80% bio-availability by I.V. injection b) I.M. administration needs sterile technique. c) I.D. injection produces local tissue necrosis and irritation d) Inhalation produces delayed systemic bioavailability

100% bioavailibility is seen in case of IV route. Sterile technique is needed in case of I.V. and I.M. administration. lrritation and local tissue necrosis is seen in case of injectable route like intramuscular or s.c. route. In inhalational route, absorption of drugs takes place from vast surfaces of alveoli-so bioavailability is high and action is very rapid.