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Pathology General 48076461

Pseudopolyps are features of -

A
Crohn's disease
B
Ulcerative colitis
C
Celiac sprue
D
Whipple's disease
High-Yield Explanation
Ulcerative colitis Ulcerative colitis is an inflammatory bowel disease characterized by - Inflammation involving only the mucosa and submucosa. Formation of pseudopolyps Involvement is in a continuous fashion (absent of skip lesions which are characteristic of CD). Ulcerative colitis involves the rectum and extends proximally in a retrograde fashion to involve the entire colon (pancolitis) in more severe cases. UC is associated with HLA-DR2, polymorphism in IL-10 gene and an abnormal T-cell response particularly of CD4 T-cells (T H2 cells).

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