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Pathology General 47d72d4b

The condition which characteristically shows bone infarcts is:

A
Iron deficiency anaemia
B
Thalassemia
C
Sickle cell anaemia
D
Hereditary spherocytosis
High-Yield Explanation
Bone marrow infarcts are frequent causes of pain in sickle cell anaemia. The heads of the femur and humerus are susceptible to avascular necrosis, a potential source of constant pain and disability. Ischemic bone becomes susceptible to bacterial osteomyelitis. Joint effusions and occasionally hemahrosis may be seen adjacent to infarcted bones. Ref: Kato G.J., Gladwin M.T. (2005). Chapter 108. Sickle Cell Disease. In J.B. Hall, G.A. Schmidt, L.D. Wood (Eds), Principles of Critical Care, 3e.

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