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Surgery General Surgery 47bf586b

All of the following are true about tumors associated with BRCA-1 except:

A
Hormone receptor positive
B
Poorly differentiated
C
Chromosome -17
D
Early age onset
High-Yield Explanation
Tumors associated with BRCA-1 are hormone receptor negative. BRCA-1 BRCA-2 * Chromosome: 17 * Chromosome: 13 * BRCA-1 associated breast cancers: * BRCA-2 associated cancers: - Invasive ductal carcinomas - Invasive ductal carcinomas - Poorly differentiated - Well differentiated - Hormone-receptor negative - Hormone-receptor positive - Early age of onset - Early age of onset - Bilateral - Bilateral * Associated ovarian, colon and prostate cancers. * Associated ovarian, colon, prostate, pancreas, gall- bladder, stomach cancers and melanoma.

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