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Biochemistry General 47b22a2d

Full form of LCAT is ?

A
Lecithin cholesterol acyl transferase
B
Lecithin cholesterol alkyltransferase
C
Lecithin choline acetyltransferase
D
Lecithin choline alcohol transferase
High-Yield Explanation
Ans. is 'a' i.e., Lecithin cholesterol acyl transferase Lecithin-cholesterol acyl transferase (LCAT) is present in HDL and esterifies the cholesterol in HDL. Major activator of LCAT is Apo-Al. Apo-C1 can also activate LCAT.HDL-Cholesterol appears to be the best independent predictor of coronary aery disease (inverse relationship) than any other known risk factor. That means low HDL is a much stronger predictor of coronary aery disease than increased LDL cholesterol or increased total cholesterolThe intracellular cholesterol activates the intracellular enzyme acyl-CoA cholesterol acyl transferase (ACAT). This enzyme catalyzes transfer of an acyl group from a fatty acid derivative to cholesterol, resulting in the formation of esterified choleserol, and this cholesterol ester is stored for subsequent use.

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