Patient with chronic hypeension will show following changes on histology of kidney

Ans. is 'a' i.e., Hyaline aeriosclerosis Hypeension is associated with two forms of small blood vessels disease ? 1. Hyaline aeriolosclerosis There is homogenous, pink, hyaline thickening of aeriolar wall. The lumen becomes narrow. It is characteristic of benign hypeension. It may also occur in diabetes and aging. 2. Hyperplastic aeriosclerosis It is characteristic of malignant hypeension. There is concentrentic, laminated thickening of aeriolar wall - onion skinning. There is mucinous intimal thickening and fibrous intimal thickening. There may be accompanied fibrinoid deposits with necrosis of the vessels wall - fibrinoid necrosis (or necrotizing aeriolitis). Favoured sites for hyperplastic aeriosclerosis are kidney, small intestine, gall bladder, peripancreatic fat, and periadrenal fat. Beside these hypeension also causes :- Atherosclerosis in large aeries. Degenerative changes in the walls of large and medium aeries that potentiate both aoic dissection and cerebrovascular hemorrhage.