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Physiology General 476d0f96

Which set of hormones have nuclear receptor:

A
Estrogen, Thyroxin & Glucagon
B
Estrogen, Thyroxin & TSH
C
Estrogen, TSH & Gonadotropin releasing hormone (GnRH)
D
Retinoic acid, Thyroxin & Luteinizing hormone (LH)
High-Yield Explanation
D i.e. Testosterone, coisol & Estogen (nearest answer)Nuclear receptors (Steroid receptors) that bind specific ligands (eg estrogen) & alter the rate at which specific genes are transcribed or translate. (Lehninger)Group I hormones eg retinoic acid, estrogen, vitamin D, glucocoicoids etc bind to nuclear receptor (Harper)Glucagon, TSH, GnRH &LH all bind to cell surface receptorsThe steroid hormones (estrogen, progesterone, and coisol for example), retinoic acid and thyroid hormones exe at least pa of their effects by a mechanism fundamentally different from that of other hormones: they act in neucleus to alter gene expression (Lehninger-456)

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