When carcinoma of stomach develops secondarily to pernicious anemia, it is usually situated in the ?

Ans. is `d' i.e., Fundus Pernicious anemia is associated with autoimmune atrophic gastritis affecting the fundic glands. Intestinal metaplasia (premalignant for gastric carcinoma),is charachterstically seen in this area of atrophic gastritis. Atrophic glands with extensive intestinal metaplasia are most charachteristically confined to the fundus in patients with pernicious anaemia.