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Medicine Endocrinology 47333eb2

Which of the following statements about Pseudohypoprathyroidismistrue-

A
Caused by 'Gain of!ftmction' inherited mutation in Gsa subunit
B
Decreased formation of cyclic GMP is observed
C
Decreased formation of Inositol triphosphate is observed
D
Decreased formation of c-AMP is observed
High-Yield Explanation
decreased urinary cyclic AMP responses to PTH , presumably with a post -GS alpha defect in adenyl cyclase stimulation ( Harrison 17 pg 2394)

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