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Pharmacology C.N.S 4731d906

Lithium is used in a pregnant woman. Which of the following congenital anomaly occurs in foetus:

A
Tetralogy of Fallot's
B
Tricuspid atresia
C
Ebstein anomaly
D
Pulmonary stenosis
High-Yield Explanation
Ans. is 'c' Ebstein's Anomaly Intake of lithium causes Ebstein's anomaly in fetus.Other important Teratogenic drugs :ACE Inhibitor-Renal damagePhenytoin*-Fetal hydantoin syndrome, hypoplasia of distal phalangesValproic acid*-Neural tube defectsThalidomide*-PhocomeliaEthanol*-Risk of fetal alcohol syndrome and alcohol related neurodevelopmental defects.Isotretinoin*-Neural tube defect*Cleft palate*ASD*Microcephaly*Warfarin*-Conradi's syndrome *Craniofacial anomalies*Chondrodysplasia punctata

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