Radiology General 4731d3a2 Which one of the following is the earliest radiographic manifestation of childhood leukemia? A Radiolucent transverse metaphyseal band B Diffuse demineralization of bones C Osteoblastic lesions in skull D Parenchymal pulmonary lesions on chest films High-Yield Explanation Metaphyseal translucencies are the earliest and most characteristic features of childhood leukemia