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Pediatrics General 471de8da

ALL L3 morphology is a malignancy arising from which cell lineage –

A
Mature B cell
B
Precursor B cell
C
Immature T cell
D
Mixed B cell & T cell
High-Yield Explanation
Cellular classification of ALL French-American-British (FAB) system divides ALL into three morphological subtypes. i) LI lymphoblasts Most common type (80-85%) Cells have scanty cytoplasm and inconspicuous nucleoli. Have better prognosis ii) L2 lymphoblasts Cells are large and more pleomorphic in size with more abundant cytoplasm and prominent nucleoli. iii) L3 - lymphoblast Least common Morphology is identical to urkitt's lymphoma cells i.e., mature B cells with surface immunoglobulin positive.

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