Surgery General 46e44460

The main barrier for diffusion of LA is:

Epineurium

Endoneurium

Perineurium

All of the above.

High-Yield Explanation

The main barrier for diffusion of LA is the perineurium. Endoneurium / Nerve membrane is the acute site of action and depend on lipid solubility of drug.

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The main barrier for diffusion of LA is:

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