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Pharmacology CHF, Angina Pectoris and Myocardial Infarction 46ac4c8c

Which of the following drug is contraindicated in variant angina?

A
Diltiazem
B
Nitrates
C
Propranolol
D
Verapamil
High-Yield Explanation
Variant angina is caused by coronary vasospasm DOC:Sublingual Nitroglycerine Prophylaxis : Calcium channel blockers (like verapamil and Diltiazem) and nitrates Beta blockers are avoided as they may precipitate coronary vasospasm by counteracting beta 2 mediated coronary vasodilation. Therefore they are avoided in variant angina.

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