All are true about typhoid ulcer except
High-Yield Explanation
Refer Robbins page no Pg 9/e 789 Clinical features Classic features are fever, abdominal pain and hematochezia First week of illness: rising ("stepwise") fever associated with chills, although frank rigors are rare Also relative bradycardia or pulse-temperature dissociation is common Second week of illness: abdominal pain develops and "rose spots" (faint salmon- colored macules on the trunk and abdomen) may be seen Third week of illness: hepatosplenomegaly, intestinal bleeding and perforation due to ileocecal lymphatic hyperplasia of the Peyer's patches may occur, together with secondary bacteremia and peritonitis ( Perforation is four times more common in males than females (Chronic Salmonella carriage is defined as excretion of the organism in stool or urine >12 months after acute infection Diagnosis Classical clinical features above Typhoid fever is diagnosed by blood or stool culture Bone marrow culture is the most sensitive test available (<a class="bl" style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: bold; font-stretch: inherit; font-size: 9pt; line-height: inherit; font-family: inherit; veical-align: baseline; color: ; overflow-wrap: break-word;" href=" 1975; 1:1211</a>), as it remains positive even after 5 days of antibiotic therapy.