Superior orbital fissure syndrome - following nerves are affected -

Ans. is 'c' i.e., C.N. 3, 4, 5, 6 o The superior orbital fissure is a cleft between the lesser and greater wing of sphenoid.The structures passed through superior orbital fissure are 3rd, 4th, 6th nerve, ophthalmic division of 5th nerve, superior & inferior division of ophthalmic vein and sympathetic fibres. Therefore symptoms of superior orbital fissure syndrome are same as in cavernous sinus thrombosis, i.e., painful ophthalmoplegia :- Pain (retro-orbital pain) and sensory> disturbances in the V1 (ophthalmic division of 5th nerve)distributionIpsilateral ophthalmoplegia (3rd, 4th and 6th nerve involvement).