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Gynaecology & Obstetrics General 4625cdf4

17-year-old girl with amenorrhea, atrophied breast, hypoplastic uterus:

A
Turner's syndrome
B
Gonadal dysgenesis
C
Androgen insensitivity syndrome
D
Klinefelter's syndrome
High-Yield Explanation
Here the patient is 17 years old and has amenorrhea (i.e. Primary Amenorrhea) with atrophied breast and hypoplastic uterus. Hypoplastic uterus can be seen in case of: • In klienefelter syndrome – Gonada are testis and not ovaries. The patient externally resembles a male and not female. Uterus is also absent. • In pure Gonadal dysgenesis. Uterus and cervix are present but infantile and there is some development of secondary sexual characteristics and a few episodes of bleeding (Leon speroff 8th/ed p1040) • In Androgen Insensitivity Syndrome – uterus is absent but breast development is normal, so it is also ruled out.

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