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Biochemistry All India exam 46238e01

Which of the following is the impoant reactive group of glutathione in its role as an antioxidant?

A
Serine
B
Sulphydryl
C
Tyrosine
D
Acetyl-CoA
High-Yield Explanation
Glutathione : lt is a tripeptide composed of 3 amino acids. Chemically, glutathione is y- glutamyl-cysteinyl-glycine. lt is widely distributed in nature and exists in reduced or oxidized states. 2G-SH =+G=S-S-G Reduced Oxidized Functions: In a steady state, the cells generally maintain a ratio of about 100/1 of CSH to G-S-S-C. The reversible oxidation- reduction of glutathione is impoant for many of its biological functions. Ref: Biochemistry by U. Satyanarayana 3rd edition Pgno : 65

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