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Pharmacology General 45a02a64

True about aminoglycoside are all except ?

A
Are bacteriostatic
B
Distributed only extracellularly
C
Excreted unchanged in urine
D
Teratogenic
High-Yield Explanation
Ans. is 'a' i.e., are bacteriostatic o Aminoglycosides are bactericidal antibiotics. o They are distributed only extracellularly so the volume of distribution is nearly equal to the extracellular fluid volume. o They are not metabolized, they are excreted unchanged in urine. o Aminoglycosides (streptomycin) should be avoided during pregnancy as they are teratogenic.

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