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Pharmacology Central Nervous system 4537a3b3

Most teratogenic in pregnancy

A
Phenytoin
B
Valproate
C
Barbiturate
D
Ethosuximide
High-Yield Explanation
Valproate is the most teratogenic, phenytoin also isn't safe. Phenobarbitone, lamotrigine, topiramate are relatively safe drugs but 4mg folic acid is required per day. Ref: KD Tripathi 8th ed.
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