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Pharmacology Chemotherapy: General Principles 452c2eb1

Which is the most active single chemotherapeutic agent in the treatment of leiomyosarcoma?

A
Adriamycin
B
Daunorubicin
C
Methotrexate
D
Cisplatin
High-Yield Explanation
Ans. (A) Adriamycin(Ref: KDT 8th/e p926)Doxorubicin (adriamycin) and daunorubicin are anthracycline derivatives.Daunorubicin is mainly used for hematological malignancies (acute leukemia) whereas doxorubicin is used for solid tumors and soft tissue sarcomas.

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