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Pediatrics General 452aad50

Which of the following infection aquired during pregnancy result in hypoplasia of limbs and scarring in the fetus?

A
Varicella
B
Herpes simplex
C
Rubella
D
Toxoplasma
High-Yield Explanation
Women who acquire VZV infection before 20 weeks of gestation have 2% risk of delivering an infant with fetal varicella syndrome. It is unlikely in women who have chickenpox during the last half of pregnancy. Clinical manifestations of congenital varicella syndrome includes: IUGR Growth retardation Limb hypoplasia Chorioretinitis Cataract Microphthalmia Cutaneous scarring Neurological abnormalities (microcephaly, hydrocephalus, horners syndrome, cranial neuropathies)

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