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Pharmacology Kidney 45247a5e

Paradoxical action among diuretics is seen with

A
Thiazide
B
Triamterene
C
Spirinolactone
D
Furosemide
High-Yield Explanation
DIURETICS ARE CONTRAINDICATED IN DIABETES IN WHICH THERE IS AN INCREASED EXCRETION OF URINE But, Thiazides are used in diabetes insipidus- paradoxical action -they create mild hypovolemia which encourages salt and water uptake in the proximal tubule and thus improve nephrogenic diabetes insipidus- action may be mediated through CAMP- poorly understood REF KD Tripathi 8th ed

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