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Pharmacology General 450dc4db

Which of the following is not true about Mebendazole?

A
Safe in pregnancy
B
Broad spectrum antihelminthic
C
Relatively low systemic bioavailability
D
Active against both larva and adult worm
High-Yield Explanation
Ans. is 'a' i.e., Safe in pregnancy "Safety of mebendazole during pregnancy is not known, but it is contraindicated on the basis of animal data". About other options o Mebendazole is a broad-spectrum antihelminthic. o Absorption of mebendazole from intestine is minimal - low bioavailability. o It is active against both larva and adult worms.

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