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Pathology General 44f8d15d

Target fibres are characteristicaly seen in a muscle biopsy of-

A
Dermatomyositis
B
Motor neuron disease
C
Myaesthenia gravis
D
Drug induced myopathy
High-Yield Explanation
Ans. is 'b' i.e., Motor neuron disease Target fibers During denervation atrophy there is cytoskeletal reorganization of some muscle cells, which results in a rounded zone of disorganized filaments in the center of the fiber (target fiber). o Amongst the given options only motor neuron disease can result in denervation of the muscle

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