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Pharmacology General 44a81232

The usual maximum dose of furosemide and spironolactone in patients with cirrhosis and poal hypeension is:

A
Furosemide 160 mg and spironolactone 400 mg
B
Furosemide 80 mg and spironolactone 400 mg
C
Furosemide 160 mg and spironolactone 200 mg
D
Furosemide 80 mg and spironolactone 200 mg
High-Yield Explanation
Usual maximum doses of diuretic for the treatment of ascites in decompensated cirrhosis are 400 mg/day of spironolactone and 160 mg/day of furosemide. Furosemide can be temporarily withheld in patients presenting with hypokalemia, which is very common in the setting of alcoholic hepatitis. Ref: HEPATOLOGY, June 2009.

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