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Pharmacology Hypolipidemic 4492c610

Statins inhibit which of the following enzyme -

A
HMG CoA reductase
B
HMG CoA synthetase
C
HMG CoA oxidase
D
Acetyl CoA synthetase
High-Yield Explanation
Ans. is 'a' i.e., HMG CoA reductase * Statins (Lovastatin) competitively inhibit the conversion of HMG-CoA to mevalonate (rate limiting step in cholesterol synthesis) by inhibiting the enzyme HMG-CoA reductase.

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