A newborn baby presented with profuse bleeding from the umbilical stump after birth. Rest of the examination and PT, APTT are within normal limits. Most probable diagnosis is-

Ans. (b) Glanzmann thrombasthenia(Ref: Robbins 9th/pg 660; 8th/pg 670)A newborn baby presented with profuse bleeding from the umbilical stump after birth.This is a case of severe inherited bleeding disorder. As PT & apTT are normal, Glanzmann thrombasthenia is the most probable cause, which can present with profuse bleeding soon after birth;It can be diagnosed by platelet aggregation studies, which will be defective.The other differential diagnosis in this scenario is Factor XIII deficiency (not given in the option)