Duchenne&;s Muscular Dystrophy is a disease of
High-Yield Explanation
Duchenne and Becker muscular dystrophy are caused by loss-of-function mutations in the dystrophin gene on the X chromosome. The encoded protein, dystrophin, is a key component of the dystrophin-glycoprotein complex.Dystrophin is thought to provide mechanical stability to the myofiber and its cell membrane during muscle contraction.Robbins 9e 1242