Which of the following is true regarding successful whole- organ pancreas transplantation in type I diabetes?
High-Yield Explanation
Whole-organ pancreas transplantation is the only therapy for type I insulin-dependent diabetes that maintains normal serum glucose levels and normal glucose tolerance tests. When the pancreas is transplanted along with a kidney, the tight glucose control generally prevents the recurrence of diabetic nephropathy. No series has shown the reversal of diabetic retinopathy or reduction in the rate of diabetic ulcers or of amputations, although some parameters of diabetic retinopathy may improve after pancreas transplantation.