Chediak - Higashi syndrome, true is:

Ans. is 'a' i.e., Defect in phagocytosis (Ref: CP Baveja, 5th/e, p. 150)* Chediak - Higashi syndrome is a rare autosomal recessive disorder that arises from a mutation of LYST gene codes for lysosomal trafficking regulator protein, which leads to a decrease in phagocytosis. Failure of phagolysosome fusion, defective chemotaxis. The decrease in phagocytosis results in recurrent pyogenic infections, partial albinism and peripheral neuropathy.