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Physiology General physiology 436357a1

Coronary blood flow to the left ventricle increases during all Except

A
Early systole
B
Myocardial hypoxia
C
Stimulation of sympathetic nerves of the hea
D
Aerial hypeension
High-Yield Explanation
During early systole, coronary blood flow falls as coronary vessels are compressed by the contracting myocardium.A fall in PO2 has a potent vasodilator effect on coronary vessels. Adenosine released from hypoxic myocardium is also a potent vasodilator.Sympathetic stimulation increases the rate and force of contraction; the resulting increase in the rate of production of vasodilator metabolites dilates coronary vessels.Myocardial work and metabolism are increased in hypeension.Ref: Guyton; 13th edition

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