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Pharmacology Anticoagulants and Coagulants 43614f2a

Apixaban is a new drug that acts by:

A
Inhibiting TNF alpha
B
Inhibiting coagulation factor Xa
C
Inhibiting platelet aggregation
D
Activating plasminogen
High-Yield Explanation
Ans. (B) Inhibiting coagulation factor Xa:(Ref: Harrison 18/e p1000, KDT 8/e p671)Rivaroxaban and Apixaban are newer oral anticoagulants that act by inhibiting factor Xa.Newer oral anticoagulants that are currently being asked in the exams are:Dabigatran (Direct thrombin inhibitor)RivaroxabanApixaban

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