Hypoglycemia is seen in
High-Yield Explanation
(D) All of the above # Hypoglycemia is seen in 1-3 per 1000 new born infants. Current definition of hypoglycemia is based on blood glucose of less than 40 mg/dL; irrespective of the gestational age, causes of hypoglycemia are given below# Transient hypoglycemia> Inadequate substrate Premature and SGA infants; Smaller of the twins Infants of diabetic mother> Relative hyperinsulinism as in infants of diabetic mothers# Persistent hypoglycemia:> Hyperinsulin states: Beta cell hyperplasia (nesidioblastosis) Adenoma of beta cells; Leucine sensitivity> Deficiency of hormones such as glucagon, hGH, epinephrine, adrenal and ACTH.> Deficiency of substrate such as in ketotic hypoglycemia and maple syrup urine disease.> Disorders of carbohydrate metabolism such as glycogen storage disease and fructose intolerance