Most common in diabetic nephropathy
High-Yield Explanation
refer Robbins 1118pgDiabetic Nephropathy The kidneys are prime targets of diabetes. Renal failure is second only to myocardial infarction as a cause of death from this disease. Three lesions are encountered: (1) glo- merular lesions; (2) renal vascular lesions, principally aeriolosclerosis; and (3) pyelonephritis, including nec- rotizing papillitis. The most impoant glomerular lesions are capillary basement membrane thickening, diffuse mesangial sclerosis, and nodular glomerulosclerosis.