A microscopic feature of seminoma include all of the following except -
High-Yield Explanation
Microscopic features of Seminoma
Sheets of uniform (monomorphic) cells, i.e., seminoma cells,
Sheets are divided into poorly demarcated lobules by delicate septa of fibrous tissue.
Septa is infiltrated with T- lymphocytes.
Sometimes prominent granuloma
Seminoma cell has the following features
Large and round to polyhedral.
Distinct cell membrane
Clear or watery appearing cytoplasm.
A large central nucleus with one or two prominent nuclei.
Cytoplasm contains glycogen.
Placental alkaline phosphatase and keratin positive.