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Pathology General 42f21852

A microscopic feature of seminoma include all of the following except -

A
Gland formation
B
Lymphocytic infiltration
C
Monomorphic cells
D
Destruction of seminiferous tubules
High-Yield Explanation
Microscopic features of Seminoma Sheets of uniform (monomorphic) cells, i.e., seminoma cells, Sheets are divided into poorly demarcated lobules by delicate septa of fibrous tissue. Septa is infiltrated with T- lymphocytes. Sometimes prominent granuloma Seminoma cell has the following features Large and round to polyhedral.                             Distinct cell membrane                                             Clear or watery appearing cytoplasm.                 A large central nucleus with one or two prominent nuclei. Cytoplasm contains glycogen.  Placental alkaline phosphatase and keratin positive.

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