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Medicine Miscellaneous 4296539a

Poland syndrome all of the following are seen except -

A
Absence of lattissimus dorsi
B
Absence of pectoralis major
C
Syndactyly of digits
D
Sho index fingers
High-Yield Explanation
Poland syndrome is a bih defect characterized by an underdeveloped chest muscle and sho webbed fingers on one side of the body.Sho ribs, less fat, and breast and nipple abnormalities may also occur on that sideTypically the right side is involved. People generally have normal movement and health The cause is unknown. One theory is that it is due to disruption of blood flow during development before bih. The condition is generally not inherited from a person's parents.No genes that contribute to the disorder have been identified. Diagnosis is based on symptoms.Often people remain undiagnosed and some may not realize they are affected until pubey. Treatment depends on the severity and may include surgical correction.About 1 in 20,000 newborns are affected. Males are affected twice as often as females. It is named after Alfred Poland who described the condition when he was a student in 1841 Signs and symptoms Abnormal gastrointestinal tract Absent pectoral muscles Brachydactyly (Sho fingers) Dextrocardia Diaphragmatic hernia/defect Humerus absent/abnormal Liver/biliary tract anomalies Maternal diabetes Oligodactyly/missing fingers Radius absent/abnormal Ref Davidson 23rd edition pg 845

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