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Medicine General 421fa43d

Lalloo, 60 years of age, a known case of cirrhosis liver, presents with increased levels of Alpha feto protein, hepatomegaly 3 cm below costal margin. USG showed lesions involving the right lobe of the liver. What is the most probable diagnosis :

A
Focal nodular hyper-plasia
B
Hepatocellular carinoma
C
Hepatic adenoma
D
Metastasis
High-Yield Explanation
Answer is B (Hepatocellular Carcinoma): Presence of elevated Alphaletoprotein levels (tumor marker) and hepatomegaly (most common clinical sign) in a sixty year old patient with cirrhosis (predisposing factor) suggests the diagnosis of hepatocellular carcinoma.

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