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Gynaecology & Obstetrics General 42142e44

Microscopic examination of a tumor shows 'Schiller Duval Bodies' which are characteristically seen in:

A
Endodermal sinus tumor
B
Choriocarcinoma
C
Granuloma cell tumor
D
Arrhenoblastoma
High-Yield Explanation
Yolk sac tumor (endodermal sinus tumor) is a germ cell tumor. The clinical presentation is similar to that of sarcoma botryoides, and the most common symptom is bloody vaginal discharge. Grossly, yolk sac tumor appears polypoid or sessile and often ulcerated. On microscopic examination, these tumors most commonly have a reticular pattern. A classic finding, although not always present, is the Schiller-Duval body. This is a papilla with a single central vessel. Ref: Hoffman B.L., Schorge J.O., Schaffer J.I., Halvorson L.M., Bradshaw K.D., Cunningham F.G., Calver L.E. (2012). Chapter 32. Vaginal Cancer. In B.L. Hoffman, J.O. Schorge, J.I. Schaffer, L.M. Halvorson, K.D. Bradshaw, F.G. Cunningham, L.E. Calver (Eds), Williams Gynecology, 2e.

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